Prof Jean-Paul Marie, MD, PhD, is Head of the Department of Otolaryngology, Head & Neck Surgery and Audiophonology at the University Hospital in Rouen, Normandy, France. He is the Head of the Experimental Surgery Laboratory, school of Medicine, and Head of the Rouen University team UR 3830 GRHVN: Research Team on the Ventilatory and Neurology Handicap. He is co-funder of a University and Hospital Federation on Regenerative Surgery (FHU Surface), conducted by Prof B. Devauchelle. He has worked on laryngeal reinnervation for several years through animal research projects, and now applies these techniques in humans. With several french surgeons (conducted by Ph Ceruse), he is involved in a research project regarding laryngeal transplantation with reinnervation, with recent application in Lyon. He regularly presents his results at international conferences and workshops and teaches the reinnervation techniques in the Rouen Medical Training Center.
His main interest is in Phonosurgery, Neurolaryngology, but also Otology and Skull base surgery. He is a member of the ELS, EGFL and American Neurolaryngology Study Group. He is also former President of the French Society of Phoniatry
Since 2013, Kate has been a consultant laryngologist at the Poole Hospital Foundation Trust on the South Coast of England. As Fellow to Professor Jean Paul Marie in Rouen, France, she learnt techniques of laryngeal reinnervation which she has continued to develop, research and introduce into the UK. A further laryngology fellowship at the RNTNE focused on airway procedures with Guri Sandhu and Phonosurgery with John Rubin. She has a comprehensive NHS laryngology service in Poole offering a laryngology treatment clinic and voice clinic. She is working at disseminating good practice and educational content via the BLA.
She is on the council of the British Laryngological Association and is passionate about improving the management of voice, airway and swallowing disorders in the UK.
Aude Lagier has been working as an ENT-phoniatrician in the University Hospital of Marseille (France) and taught anatomy at the Faculty of Medicine (Aix-Marseille University, France) until 2016. At the University Hospital of Liege (Belgium) since 2016, her clinical activity focuses on the medical and surgical management of voice and swallowing disorders, particularly in the field of laryngeal immobility surgical treatments.
She also continues to teach head and neck anatomy at the University of Liege. Her Ph.D. in sciences of language dealt with the laryngeal physiology and phonotrauma using ex vivo human larynges. She continues her research on the functional anatomy of the larynx in close collaboration with the laboratories of an anatomy of the universities of Liege (Belgium) and Aix-Marseille (France), and with the « Speech and Language Lab » (UMR 7309, CNRS-Aix Marseille University).
Unilateral and bilateral vocal fold paralysis have a totally different clinical presentation and different treatment.
The course is aimed at teaching anatomical basis and physiological knowledge, necessary to understand and treat laryngeal paralysis.
Surgical techniques of non selective and selective reinnervation will be detailed through theoretical talks and anatomical dissections. Hands on teaching will be favorized.
Nerve anastomosis will be demonstrated and microsurgical training will be proposed on several models.
Live surgery will be performed and shown to explain technical tips.
At the end of the course, all the attendants will be able to make these surgical techniques on their patients, if they have recognized the good indication.
Jean-Paul Marie – Laryngologist – CHU Rouen – France
Aude Lagier – ENT Surgeon – CH LIEGES – BELGIUM
Kate Heathcote – ENT Surgeon – United Kingdom
Frederic Crampon – ENT Surgeon – Rouen – France
Jean Selim – Anesthesiologist – CHU Rouen – France
ENT Surgeon
8:00am – 8:30am : Welcome and registration
8:30am – 8h45am : Talks (Auditorium MTC) :
• Anatomy and physiology of the larynx, applied to laryngeal
reinnervation (A. Lagier, 15’)
8:45am – 8h55am : Talks (Auditorium MTC) :
• Technique of the non selective unilateral reinnervation (ansa
recurrent technique) in unilateral vocal fold
paralysis (JP. Marie 10’)
8:55am – 9:00am : Talks (Auditorium MTC) :
• Case n°1 presentation (JP. Marie 5’)
9:00am – 10:45am : Surgery from the Operating Room (OR) :
Unilateral non selective reinnervation (ansa recurrent technique)
K. Heathcote and A. Lagier (OR), with interaction from
the auditorium : Y. Karagama, JP Marie
10:45am – 11:00am : Coffee break
11:00am – 11:10am : Talks (Auditorium MTC)
• Results of the ansa-recurrent technique and indications
(JP. Marie 10’)
11:10am – 11:20am : Talks (Auditorium MTC)
• Ansa-recurrent: UK experience (K. Heathcote, Y. Karagama 10’)
11:20am – 11:30am : Talks (Auditorium MTC)
• Discussion (live and visio conference) (10’)
11:30am – 11:45am : Talks (Auditorium MTC)
• History and principe of Selective laryngeal reinnervation in
bilateral vocal fold paralysis (JP. Marie 15’)
11:45am – 11:55am : Talks (Auditorium MTC)
• Laryngeal diplegia, etiology, evaluation and LEMG (JPM 10’)
11:55am – 12:00pm : Talks (Auditorium MTC)
• Case n°2 presentation (JP. Marie 5’)LEMG in case of laryngeal reinnervation (JP. Marie & J. Selim)
with interaction from the auditorium : K. Heathcote and A. Lagier
1:00pm – 2:00pm : Lunch and discussions (MTC)
2:00pm – 2:15pm : Talks (Auditorium MTC)
• Anesthesiology for diplegia (J. Selim – 15’)
2:15pm – 2:30pm : Talks (Auditorium MTC)
• Anatomy of the hypoglossal branches : ansa and XII TH
(F. Crampon 15’)
2:30pm – 2:45pm : Talks (Auditorium MTC)
• Anatomy and physiology of the phrenic nerve (JP. Marie, 15’)
2:45pm – 3:00pm : Talks (Auditorium MTC)
• Technique of Bilateral and selective laryngeal reinnervation
(JP. Marie 15′)
3:00pm – 3:15pm : Talks (Auditorium MTC)
• Nerves sutures (JP. Marie 10’)
3:15pm – 3:30pm : Group determination and travel to
Dissection Lab an Microsurgery-Lab in the MTC
3:30pm – 5:45pm Hands on :
Group 1 : Cervical anatomy dissection (A. Lagier, K. Heathcote,
Y. Karagama, F. Crampon)
Group 2: nerves sutures (JP. Marie, C. Maquet, P. Charnavel)
6:00pm – 6:05pm :
• Case n°3 presentation (JP. Marie 5)
6:05pm – 7:00pm : For all, from the Auditorium of MTC
• Synthesis, discussion
8:00am – 10:30am hands on :
Group 2 : Cervical anatomy, dissection (Y. Karagama, F. Crampon,
K . Heathcote, JP. Marie)
Group 1 : nerve sutures (JP. Marie, C. Maquet, P. Charnavel)
10:30am – 1:00pm : Surgery from the OR : Bilateral selective
reinnervation. Nerve identification. Intralaryngeal dissection (K.
Heatcote, A. Lagier) with interaction from the Auditorium : Y.
Karagama, JP. Marie
11:00am : Coffee break (during the surgical procedure)
1:00pm – 2:00pm : Lunch and discussions (MTC)
2:00pm – 4:00pm : Surgery from the OR : Bilateral selective
reinnervation. Nerves sutures (JP Marie). Auditorium MTC : Kate
Heathcote, Aude Lagier, Y Karagama.
4:00pm – 4:10pm :
• Location of the motor endplates inside the PCA (Aude Lagier, 10’)
4:10pm – 4:30pm :
• Bilateral reinnervation, results and indications (JP Marie,20’)
4:30pm – 6:00pm :
• Discussions
6:00pm – 6:30pm : Closing remarks
To get to MTC, Medical Training Center of Rouen from Paris, you have several transport options.
By air :
From Orly or Paris-Charles de Gaulle (CDG) airport, you can go by bus or subway go to railway station saint Lazare and then, take a train to Rouen station and then take a bus or taxi to the Medical Training Center.
By train :
You can take a train from Paris (Saint Lazare) to the station of Rouen. The journey takes about one and half hour by regional train (TER) or 1h30 by intercity train (IC). From the Rouen train station, you can take a bus (Teor – Line 4, in front of the railway station) or taxi to the Medical Training Center.
I hope this will help you plan your trip.
We suggest you book your own room at at the l’hôtel Mercure Rouen Cathedrale. You simply have to send a message by filling out this form
Rouen is a historic city located in the north-west of France, on the banks of the Seine. It is famous for its exceptionally preserved architectural heritage, including its world-renowned Gothic cathedral and the Place du Vieux-Marché, where Joan of Arc was burned alive in 1431. The city was one of the largest shopping centers in medieval France, with lively streets and picturesque half-timbered houses. Today it is home to art and history museums, contemporary art galleries, and fashion and design boutiques. The city is easily accessible by train from Paris, making it a popular destination for day trips or longer stays. With its charming cobbled streets, lively squares and beautifully preserved historic buildings, Rouen is a must-see destination for history and architecture lovers.
Medical Training Center, 20 Rue Marie Curie, 76000 Rouen
