LARYNGEAL REINNERVATION

5th and 6th of April, 2027

PROF Jean paul marie

MD, PHD - ENT SURGEON - CHU Rouen - FRANCE

Prof Jean-Paul Marie, MD, PhD, is Head of the Department of Otolaryngology, Head & Neck Surgery and Audiophonology at the University Hospital in Rouen, Normandy, France. He is the Head of the Experimental Surgery Laboratory, school of Medicine, and Head of the Rouen University team UR 3830 GRHVN: Research Team on the Ventilatory and Neurology Handicap. He is co-funder of a University and Hospital Federation on Regenerative Surgery (FHU Surface), conducted by Prof B. Devauchelle. He has worked on laryngeal reinnervation for several years through animal research projects, and now applies these techniques in humans. With several french surgeons (conducted by Ph Ceruse), he is involved in a research project regarding laryngeal transplantation with reinnervation, with recent application in Lyon. He regularly presents his results at international conferences and workshops and teaches the reinnervation techniques in the Rouen Medical Training Center.

His main interest is in Phonosurgery, Neurolaryngology, but also Otology and Skull base surgery. He is a member of the ELS, EGFL and American Neurolaryngology Study Group. He is also former President of the French Society of Phoniatry

Prof aude lagier

ENT physician-surgeon and anatomist - CH Lièges - BELGIUM

Aude Lagier has been working as an ENT-phoniatrician in the University Hospital of Marseille (France) and taught anatomy at the Faculty of Medicine (Aix-Marseille University, France) until 2016. At the University Hospital of Liege (Belgium) since 2016, her clinical activity focuses on the medical and surgical management of voice and swallowing disorders, particularly in the field of laryngeal immobility surgical treatments.
She also continues to teach head and neck anatomy at the University of Liege. Her Ph.D. in sciences of language dealt with the laryngeal physiology and phonotrauma using ex vivo human larynges. She continues her research on the functional anatomy of the larynx in close collaboration with the laboratories of an anatomy of the universities of Liege (Belgium) and Aix-Marseille (France), and with the « Speech and Language Lab » (UMR 7309, CNRS-Aix Marseille University).

PROF, YAKUBU KARAGAMA

ENT Surgeon

Mr Yakubu Karagama is a highly qualified ears, nose and throat consultant and Laryngologist working in London private practices at HCA The Shard London, BMI Blackheath Hospital London and BMI The Alexandra Hospital in Manchester. His NHS Practice is at Guy’s and St Thomas Hospital London. He leads the multidisciplinary specialist voice clinic at Guy’s and St Thomas Hospital London. He specialises in general adult and children Ear, Nose and Throat problems but in addition he has a special interest in professional voice problems, nasal and sinus problems. He is the founder and course director for London and Manchester Phonosurgery course, is keen in voice research and obtained an MSc in Advance Voice Research at the University of Newcastle-upon-Tyne in 2005. Mr Karagama has presented his research and won prizes at national and international conferences, including the North of England Otolaryngological Society, the Royal Society of Medicine and the British Association Conference of Otolaryngologists (BACO). He has authored and co-authored over 50 publications, is a visiting Senior Lecturer at King’s College, London. He was Secretary of the British Laryngological Association. He is also an Honorary Fellow at the Royal Northern College of Music Manchester.

Necati enver, md

FEBORL, Associate Professor in Otolaryngology / Istanbul Voice and Swallowing Center

Dr. Necati Enver is a laryngologist based in Istanbul and the founder of the Istanbul Voice and Swallowing Center, where he focuses exclusively on the diagnosis and treatment of complex voice, swallowing, and airway disorders. He previously served for more than 10 years at Marmara University, where he founded and expanded the Laryngology Department, established the Voice and Swallowing Clinic, and trained numerous residents and PhD students in modern laryngeal surgery and voice science.

A fellowship-trained laryngologist from NewYork–Presbyterian Hospital (Weill Cornell & Columbia University), Dr. Enver has special expertise in laryngeal reinnervation and unilateral and bilateral reinnervation surgeries for vocal fold paralysis. His current work bridges cutting-edge surgical innovation, office-based laryngeal procedures, and AI-assisted diagnostics in voice care. He also serves as Head of the Media Committee of the European Laryngological Society (ELS), contributing to international education and collaboration in laryngology.

Aims of the Laryngeal reinnervation Workshop

Unilateral and bilateral vocal fold paralysis have a totally different clinical presentation and different treatment.

The course is aimed at teaching anatomical basis and physiological knowledge, necessary to understand and treat laryngeal paralysis.

Surgical techniques of non selective and selective reinnervation will be detailed through theoretical talks and anatomical dissections. Hands on teaching will be favorized.

Nerve anastomosis will be demonstrated and microsurgical training will be proposed on several models.

Live surgery will be performed and shown to explain technical tips.

At the end of the course, all the attendants will be able to make these surgical techniques on their patients, if they have recognized the good indication.

 

Speakers

  • Jean-Paul Marie – Laryngologist – CHU Rouen – France
  • Aude Lagier – ENT Surgeon – CH LIEGES – BELGIUM
  • Kate Heathcote – ENT Surgeon – United Kingdom
  • Yakubu Karagama – ENT Surgeon – United Kingdom
  • Frederic Crampon – ENT Surgeon – Rouen – France
  • Jean Selim – Anesthesiologist – CHU Rouen – France
  • Necati Enver – Laryngologist – Istanbul

Public

ENT Surgeon

PRICE

  • 1600€ per person for hands on
  • 1000€ per person for observer

DAY 1

8:00am : Welcome and registration
8:30am – 9:30am : Talks 

  • Introduction (Jean-Paul Marie, 10’)
  • Anatomy and physiology of the larynx, applied to laryngeal reinnervation (Aude Lagier, 15’)
  • Technique of the non-selective unilateral reinnervation (ansa-recurrent technique) in unilateral vocal fold paralysis (Jean-Paul Marie, 10’)
  • Presentation of Virtual Case n°1 (Jean-Paul Marie, 5’)

9:20am – 10:45am : Prerecorded films: Unilateral non selective reinnervation (ansa recurrent technique, Jean-Paul Marie), with interaction with the attendants and faculty

10:45am – 11:00am : Coffee Break

11:00am – 12:45pm :

  • Results of the ansa-recurrent technique, and indications (Jean-Paul Marie 15’)
  • Turkey experience in unilateral vocal fold paralysis (Necati Enver 10’)
  • Non selective unilateral reinnervation in children, long term experience (Marshall Smith, 15’)
  • EMG practice (Yakubu Karagama 15’)
  • Adductor muscles reinnervation in some dysphonia (Yakubu Karagama 10’)
  • Laryngeal diplegia, etiology, evaluation and LEMG (Jean-Paul Marie 10’)
  • Virtual Case n°2 presentation (Jean-Paul Marie 5’)
  • Virtual case Film on Evaluation of diplegia with LEMG in case of laryngeal reinnervation (JP Marie 10’), with interaction with the attendants and faculty

12:45pm – 2:00pm : Lunch break

2:00pm – 3:15pm : Talks 

  • History and Principle of Selective laryngeal reinnervation in bilateral vocal fold paralysis (Jean-Paul Marie 15’)
  • Anatomy of the hypoglossal branches: ansa and XII TH (Frédéric Crampon 15’)
  • Anatomy and physiology of the phrenic nerve (Jean-Paul Marie, 10’)
  • Nerve sutures (Jean-Paul Marie 10’)
  • Technique of Bilateral and Selective laryngeal reinnervation (JP Marie 15’)

3:15pm – 6:00pm : Dissection Lab and Microsurgery Lab in the MTC (for Hands on. Observers can be present) Hands on – Group 1: Cervical anatomy, dissection (A Lagier, Y Karagama, N Enver, M Smith); Group 2: Nerve sutures (JP Marie, Residents).

6:00pm – 6:30pm : For all, from the Auditorium : 

  • Synthesis, discussion

DAY 2

8:00am – 10:15am : Talks and films

  • Early experience with bilateral selective reinnervation (Necati Enver 15’)
  • US experience of bilateral selective reinnervation (Marshall Smith 15’)
  • Case n°3 (Virtual Bilateral selective reinnervation) presentation (Jean-Paul Marie 5’)

Virtual surgery with Films of Bilateral selective reinnervation. Nerves identification and Intralaryngeal dissection (JP Marie), with interaction with the attendants and faculty

10:15am – 10:30am : Coffee break

10:30am – 1:15pm : Hands on : In the MTC Surgical Room: Group 2: Cervical anatomy, dissection (A Lagier,N Enver, Y Karagama, JP Marie); Group 1: Nerve sutures (JP Marie and Rouen Team). Group 3: Nerve sutures (JP Marie and Rouen Team).

1:15pm – 2:15pm : Lunch break 

2:15pm – 3:30pm : Prerecorded surgery:  Bilateral selective reinnervation. Nerves sutures (JP Marie)  with interaction with the attendants and faculty

3:30pm – 5:00pm : 

  • Anesthesiology for diplegia (Vanessa Korkomaz, Jean Selim 15’)
  • Location of the motor endplates inside the PCA (Aude Lagier 10’)
  • Bilateral reinnervation, results and indications (Jean-Paul Marie 20’)
  • Discussions (30’)

5:15pm – 5:45pm : Closing remarks 

 

Registration form

Plan your trip

To get to MTC, Medical Training Center of Rouen from Paris, you have several transport options.

By air :

From Orly or Paris-Charles de Gaulle (CDG) airport, you can go by bus or subway go to railway station saint Lazare and then, take a train to Rouen station and then take a bus or taxi to the Medical Training Center.

By train :

You can take a train from Paris (Saint Lazare) to the station of Rouen. The journey takes about one and half hour by regional train (TER) or 1h30 by intercity train (IC). From the Rouen train station, you can take a bus (Teor – Line 4, in front of the railway station) or taxi to the Medical Training Center.

I hope this will help you plan your trip.

Your hotel

We suggest you book your own room at at the l’hôtel Mercure Rouen Cathedrale. You simply have to send a message by filling out this form

City of Rouen

Rouen is a historic city located in the north-west of France, on the banks of the Seine. It is famous for its exceptionally preserved architectural heritage, including its world-renowned Gothic cathedral and the Place du Vieux-Marché, where Joan of Arc was burned alive in 1431. The city was one of the largest shopping centers in medieval France, with lively streets and picturesque half-timbered houses. Today it is home to art and history museums, contemporary art galleries, and fashion and design boutiques. The city is easily accessible by train from Paris, making it a popular destination for day trips or longer stays. With its charming cobbled streets, lively squares and beautifully preserved historic buildings, Rouen is a must-see destination for history and architecture lovers.

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